ColdFlu Formula
ColdFlu Formula la Raceala si Gripa
ColdFlu Formula cu Germaniu Organic (GE-132) la activitatea
antivirala
1. Necesitatea folosirii Vitaminei C Acid ascorbic.
2. Evidenta significanta despre Vitamina C la raceala.
3 N-Acetilcisteina inbunatateste
respiratia este un mucolitic cu efect bronhodilatator indicat la
bronsitele
acute si cronice, studiu randomizat, dublu-orb, placebo controlat
+
Vitamina D3 1000U.I. 1 Fl
de 30 Capsule
6. Vitamina D cu uz in practica clinica
Incidenta de raceala si gripa in timpul iernii
7. Vitamina D la infectii
8. Cu varsta scade capacitatea organsimului de a produce D3
Vitamina D cu functie autocrina si endocrina
9. Vitamina D3 imunomodulator in interactiune cu sistemul imunitar,
mediaza imunologic la receptorul de Vitamina D (VDR)
| Vit C: Structura chimica |
 |
| Vit C - Acid Ascorbic: Formula moleculara:
C6H8O6 |
| Vit C - Acid Ascorbic: Greutatea moleculara:
176.13 |
11. Vitamina C participa la cresterea sintezei de colagen in
tesuturi
12. Vitamina
C si colesterolul, re-evaloarea Vitaminei C
| Re-evaluarea Vitaminei C |
 |
13. Directia
unei noi recomandari RDA pentu tinere femei
15. Vitamina
C inhiba oxidarea lipoproteinele cu densitate joasa - LDL si ateroscleroza
- Liproproteina(a) are efect de lipire (Adeziune) de peretii vasculari,
a moleculei LDL (Low Density Lipoprotein) a depunerilor de molecule de Calciu
si molecule de Zahar (glucoza).
| Placa aterosclerotica cu tromb |
 |
Cardiopatia ischemica poate fi produsa de cauze organice cum ar
fi:
Leziuni in peretii vasculari datorita oxidatiei din insuficienta a antioxidantilor
pentru reducerea radicalilor liberi, Coenzima Q10 este un antioxidant puternic.
- Din lipsa cronica de Vitamina C peretii vasculari primesc leziuni
iar efectele de reparatie a organizmului compenseaza necontrolat cresterea
cu celule musculare
Depunerilor cu Lipoproteina(a) = apoa in placa aterosclerotica.
| Placa aterosclerotica |
 |
17. Concentatia
serica de Vitamina C este invers proportional cu incidenta accidentului vascular
cerebral
18. Vitamina
C ca antioxidant, scaderea riscului bolilor coronariene la femei
19. Vitamina
C, Vitamina E cu reducerea riscului bolilor coronariene
si a mortalitatii persoanelor in virsta
20. Vitamina
C cu administrare pe durata lunga reface disfunctia endoteliala la pacienti
cu boli coronariene
22. Efectul
Vitaminei C ca antioxidant la infarctul miocardic acut
| Antioxidantii neutralizeaza radicali liberi |
 |
Neutralizarea
de radicali liberi - Densitatea
Neutralizarea de radicali liberi - Capacitate scazuta
- Suficienti antioxidanti de recomandat:
Acid alfa lipoic, Ceai Verde, Vitamina C, Glutation, Vitamin E, Carotenoizi,
Coenzima Q10 sau enzime antioxidante ca superoxid dismutaza
(SOD) care detoxifica radicalul superoxid, peroxidul de hidrogen (H 2O2)
si Glutation peroxidaza (GPx) care detoxifica peroxizii celulari
- Spirulina contine superoxid dismutaza (SOD) un antioxidant puternic
110000 Unitati/100g
Neutralizarea de radicali liberi - Capacitate suficienta
23. Vitamina
C in tratamentul hipertensiunii, studiu randomizat dublu orb placebo controlat
24. Vitamina
C inbunatateste endoteliul - dependent de vasodilatatie la restaurarea oxidului
nitric si esential la hipertensiune
Vitamina C inbunatateste endoteliul - dependent
de vasodilatatie la restaurarea oxidului nitric si esential la hipertensiune
|
|
|
25. Vitamina
C inbunatateste circulatia singelui
27. Vitamina
C inbunatateste activitatea cardiovasculara si microcirculatia la
fumatori
28. Cine fumeaza trebuie sa isi asigure aportul de Vitamina C care previne
producerea daunei oxidative prin radicalii liberi,
cauzata de fumat
29. Vitamina
C la infectiile acute respiratorii
32. Suplimente nutritive
cu Vitamina C ca suport la boala de cancer si prelungirea supravietuirii
umane la cancer
33. Vitamina C
cu doza inalta in tratamentul pacientilor de cancer unde nu are prioritate
citostaticele, studiu randomizat, dublu-orb, placebo controlat
34. Vitamina C
cu doza inalta in tratamentul helicobacter pylori
35. Vitamina C
- Farmacocinetica la implicarea folosirii orale si intravenoase
36. Vitamina C
inhiba cresterea bacteriala de helicobacter pylori, factor cu risc la cancerul
gastric
37. Interactiune
intre Vitamina C si Seleniu inhiba cresterea cancerului mamar
38. Vitamina C
inbunatateste activitatea la doxorubicina, cisplatin si paclitaxel in cancerul
mamar
39. Vitamina
C imunomodulator la infectia celulara HIV
40. Vitamina
C pe durata lunga previne cataracta cu cristalin opac
42. Vitamina
C previne cataracta la persoanele in virsta
| Pacientul acopera un ochi si priveste punctul daca vederea devine
ondulatorie poate fi caz de degenerescenta maculara. |
Degenerescenta maculara |
 |
 |
43. Vitamina C cu potential efect preventiv
de degenerescenta maculara (AMD)
44. O portocala pe zi tii pe doctor
departe
| O portocala pe zi, tii pe doctor departe - Suplimente nutritive
cu Vitamina C |
 |
45. Vitamina
C referinte
de administrare
Terapia Anti Aging:
 Anti-Aging-Systeme
- Formula
AntiAging
Bibliografie - Referinte ColdFlu Formula
Informatii din bibliografia electronica la tema: Nutritie si sanatate
1. Pauling L. Evolution and the need for ascorbic acid. Proc Natl Acad SciUSA.
1970; 67:1643-1648.
2. Pauling L. The significance of the evidence about ascorbic acid and the common
cold. Proc
Natl Acad SciUSA. 1971; 68:2678-2681.
- Douglas RM, Hemila H, D'Souza R, Chalker EB, Treacy B. Vitamin C for preventing
and treating the common cold. National Centre for Epidemiology and Population
Health, Australian National University, 34 Nungara Place, Aranda, ACT, Australia,
2614. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD000980.
- Pauling LC. Vitamin
C and the Common Cold. San Francisco: W. H. Freeman; 1970.
3 Long-term
oral acetylcysteine in chronic bronchitis: Adouble-blind controlled study.Multicenter
Study GroupEur. J. Respir. Dis. 61(Sup.):93 (1980)
4. Aso H, Suzuki F, Ebina
T, Ishida N. Antiviral activity of carboxyethylgermanium sesquioxide (Ge-132)
in mice infected with
influenza virus. Department of Bacteriology, Tohoku University School of
Medicine, Sendai, Japan. J Biol Response Mod. 1989
Apr;8(2):180-9.
5. Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB, Madronich S, Garland CF,
Giovannucci E. Epidemic influenza and vitamin D. Atascadero State Hospital, 10333
El Camino Real, Atascadero, CA 93422, USA. Epidemiol Infect. 2006 Dec;134(6):1129-40.
Epub 2006 Sep 7.
6. Cannell JJ, Hollis BW. Use of vitamin D in clinical practice. Altern Med Rev.
2008 Mar;13(1):6-20.
7. Zasloff M. Fighting infections with vitamin D. Nat Med. 2006
Apr;12(4):388-90.
8. MacLaughlin J, Holick MF. Aging decreases the capacity of human
skin to produce vitamin D3. J Clin Invest. 1985 Oct;76(4):1536-8.
9.
Manolagas SC, Provvedini DM, Tsoukas CD. Interactions of 1,25-dihydroxyvitamin
D3 and the immune system. Mol Cell Endocrinol. 1985 Dec;43(2-3):113-22.
10. Levine
M, Rumsey SC, Daruwala R, Park JB, Wang Y. Criteria and recommendations for vitamin
C intake. Molecular and Clinical Nutrition
Section, Digestive Diseases
Branch, National Institute of Diabetes and Digestive and Kidney Diseases,
National Institutes
of Health, Bethesda, MD 20892, USA. JAMA. 1999 Apr 21;281(15):1415-23.
11. Rowe DJ, Ko S, Tom XM, Silverstein SJ, Richards DW. Enhanced production
of mineralized nodules and collagenous proteins in vitro by calcium ascorbate
supplemented
with vitamin C metabolites. Department of Dental Public Health and Hygiene,
School of Dentistry, University of California, San Francisco 94143-0754,
USA. djrowe@itsa.ucsf.edu
J Periodontol. 1999 Sep;70(9):992-9.
12. Ginter E 1977. the Role of Vitamin C and Cholesterol, in Re-evaluation
of Vitamin C Hrsg. A. Hanck und G. Ritzel, H. Huber, Bern S. 53-56
- Fidanza, A. et al. Vitamin C and cholesterol. Int. J. Vit. Nutr. Res. 1982;
23:153-171.
13. Carr AC, Frei B. Toward a new recommended dietary allowance for vitamin
C based on antioxidant and health effects in humans. Linus Pauling Institute,
Oregon
State University, Corvallis
97331, USA. Am J Clin Nutr. 1999 Jun;69(6):1086-107.
- Levine M, Wang Y, Padayatty SJ, Morrow J. A new recommended dietary allowance
of vitamin C for healthy young women. Molecular and Clinical Nutrition Section,
Digestive Diseases Branch, National Institute of Diabetes and Digestive and
Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-1372,
USA. markl@intra.niddk.nih.gov
Proc Natl Acad Sci U
S A. 2001 Aug 14;98(17):9842-6.
14. Ginter E, Cerna O, Budlovsky J, Balaz V, Hruba F, Roch V, Sasko E. Effect
of ascorbic acid on plasma cholesterol in humans in a long-term experiment.
Int J Vitam Nutr Res. 1977;47(2):123-34.
- Hornig, D., Weiser, H. Ascorbic acid and cholesterol: effect of graded
oral intakes on cholesterol conversion to bile acid in guinea-pigs. Experientia.
1976 Jun 15;32(6):687-9.
15. Hwang J, Peterson H, Hodis HN, Choi B, Sevanian A. Ascorbic acid enhances
17 beta-estradiol-mediated inhibition of oxidized low density lipoprotein
formation. Department of Molecular Pharmacology and Toxicology, School of
Pharmacy, University
of Southern California, 1985 Zonal Avenue, PSC 612, 90033, Los Angeles, CA,
USA. julianah@hsc.usc.edu Atherosclerosis. 2000 Jun;150(2):275-84.
- Jialal, I., Fuller, C.J. Effect of vitamin E, Vitamin C and beta-carotene
on LDL oxidation and atherosclerosis. Canad. J. Cardiol. 1995; 11, (Suppl
G): 97-103.
16. Valkonen MM, Kuusi T. Vitamin C prevents the acute atherogenic effects
of passive smoking. Department of Medicine, University of Helsinki, Helsinki,
Finland.
Free Radic Biol Med. 2000 Feb 1;28(3):428-36.
17. Yokoyama T, Date C, Kokubo Y, Yoshiike N, Matsumura Y, Tanaka H. Serum
vitamin C concentration was inversely associated with subsequent 20-year
incidence of
stroke in a Japanese rural community. The Shibata study. Department of Epidemiology,
Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Stroke. 2000 Oct;31(10):2287-94.
18. Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Hu FB, Manson JE, Willett
WC. Vitamin C and risk of coronary heart disease in women. Department of
Medicine, Children's Hospital, Boston, Massachusetts, USA. stavroula.osganian@TCH.harvard.edu
J Am
Coll Cardiol. 2003 Jul 16;42(2):246-52.
- Knekt P, Ritz J, Pereira MA, O'Reilly EJ, Augustsson K, Fraser GE, Goldbourt
U, Heitmann BL, Hallmans G, Liu S, Pietinen P, Spiegelman D, Stevens J, Virtamo
J, Willett WC, Rimm EB, Ascherio A. Antioxidant vitamins and coronary heart
disease risk: a pooled analysis of 9 cohorts. National Public Health Institute,
Helsinki,
Finland. paul.knekt@ktl.fi Am J Clin
Nutr. 2004 Dec;80(6):1508-20.
19. Losonczy KG, Harris TB, Havlik RJ. Vitamin E and vitamin C supplement
use and risk of all-cause and coronary heart disease mortality in older persons:
the Established Populations for Epidemiologic Studies of the Elderly. Epidemiology,
Demography and Biometry Program, National Institute on Aging, Bethesda, MD
20892-9205, USA. klosoncz@gibbs.oit.unc.edu
Am J Clin Nutr. 1996 Aug;64(2):190-6.
20. Gokce N, Keaney JF Jr, Frei B, Holbrook M, Olesiak M, Zachariah BJ, Leeuwenburgh
C, Heinecke JW, Vita JA. Long-term ascorbic acid administration reverses
endothelial vasomotor dysfunction in patients with coronary artery disease.
Evans Memorial
Department of Medicine, Cardiology Section, and Whitaker Cardiovascular Institute,
Boston University School of Medicine, Boston, MA, USA. Circulation. 1999
Jun 29;99(25):3234-40.
21. Collins R, Peto R, Armitage J. The MRC/BHF Heart Protection Study: preliminary
results. Oxford Clinical Trials Service Unit. Int J Clin Pract. 2002 Jan-Feb;56(1):53-6.
22. Chamiec, T., Herbaczynska-Cedro, K., Ceremuzynski, L. Effects of antioxidant
vitamin C and E on signal-averaged electrocardiogram in acute myocardial
infarction Am.
J. Cardiol.1996; 77, 4: 237-241.
- Jha, P., et al., "The Antioxidant Vitamins and
Cadiovascular
Disease," Ann. Of Intern. Med., vol. 123 (1995), pp. 860.
23. Duffy SJ, Gokce N, Holbrook M, Huang A, Frei B, Keaney JF Jr, Vita JA.
Treatment of hypertension with ascorbic acid. Lancet. 1999 Dec 11;354(9195):2048-9.
-
Ness AR, Chee D, Elliot P. Vitamin C and blood pressure—an overview.
J Hum Hypertens. 1997; 11:343-350.
24. Taddei S, Virdis A, Ghiadoni L, et al. Vitamin C improves endothelium-dependent
vasodilation by restoring nitric oxide activity in essential hypertension.
Circulation. 1998; 97:2222-2229.
25. Simon JA, Hudes ES. Relationship of ascorbic acid to blood lead levels.
Department of Epidemiology and Biostatistics, University of California, Veterans
Affairs
Medical Center, San Francisco 94121, USA. jasimon@itsa.ucsf.edu JAMA. 1999
Jun 23-30;281(24):2289-93.
26. Dawson EB, Evans DR, Harris WA, Teter MC, McGanity WJ. The effect of
ascorbic acid supplementation on the blood lead levels of smokers.
Department of Obstetrics & Gynecology, the University of Texas Medical
Branch at Galveston, 77555-0587, USA. J Am Coll
Nutr. 1999 Apr;18(2):166-70.
27. Gamble J, Grewal PS, Gartside IB. Vitamin C modifies the cardiovascular
and microvascular responses to cigarette smoke inhalation in man. School
of Sport
and Exercise Sciences, Birmingham University, Birmingham B15 2TT, U.K. john.gamble@virgin.net
Clin Sci (Lond).
2000 Apr;98(4):455-60.
28. Panda K, Chattopadhyay R, Ghosh MK, Chattopadhyay DJ, Chatterjee IB.
Vitamin C prevents cigarette smoke induced oxidative damage of proteins and
increased
proteolysis. Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology
and the Department of Biochemistry, University College of Science, Calcutta,
India. Free Radic Biol Med. 1999 Nov;27(9-10):1064-79.
29. Hemila H, Douglas RM. Vitamin C and acute respiratory infections. Int
J Tuberc Lung Dis. 1999; 3:756-761.
30. Bucca C, Rolla G, Oliva A, Farina JC. Effect of vitamin C on histamine
bronchial responsiveness of patients with allergic rhinitis. Dpt. di Scienze
Biomediche
e Oncologia Umana, Universita di Torino,
Italy. Ann Allergy. 1990 Oct;65(4):311-4.
31. Fortner BR Jr, Danziger RE, Rabinowitz PS, Nelson HS. The effect of ascorbic
acid on cutaneous and nasal response to histamine and allergen. J Allergy
Clin Immunol. 1982 Jun;69(6):484-8.
32. Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment
of cancer: Prolongation of survival times in terminal human cancer. Proc
Natl Acad Sci U S A. 1976 Oct;73(10):3685-9.
33. Moertel CG, Fleming TR, Creagan ET, Rubin J, O'Connell MJ, Ames MM. High-dose
vitamin C versus placebo in the treatment of patients with advanced cancer
who have had no prior chemotherapy. A randomized double-blind comparison.
N Engl
J Med. 1985 Jan 17;312(3):137-41.
34. Jarosz M, Dzieniszewski J, Dabrowska-Ufniarz E, et al. Effects of high
dose vitamin C treatment on Helicobacter pylori ingestion and total vitamin
C concentration
in gastric juice. Eur J Cancer Prev. 1998; 7:449-454.
35. Padayatty SJ, Sun H, Wang Y, Riordan HD, Hewitt SM, Katz A, Wesley RA,
Levine M. Vitamin C pharmacokinetics: implications for oral and intravenous
use. National
Institute of Diabetes and Digestive and Kidney Diseases, the National Cancer
Institut, and the Clinical Center, National Institutes of Health, Bethesda,
Maryland 20892-1372,
USA. Ann Intern Med. 2004 Apr 6;140(7):533-7.
36. Zhang HM, Wakisaka N, Maeda O, Yamamoto T. Vitamin C inhibits the growth
of a bacterial risk factor for gastric carcinoma: Helicobacter pylori. Department
of Infectious Disease and Tropical Medicine, Research Institute International
Medical Center of Japan, Tokyo. Cancer. 1997 Nov 15;80(10):1897-903.
37. Ip C. Interaction of vitamin C and selenium supplementation in the modification
of mammary carcinogenesis
in rats.
J Nat Cancer Inst. 1986; 77:299-303.
- Zhang S, Hunter DJ, Forman MR, Rosner BA, Speizer FE, Colditz GA, Manson
JE, Hankinson SE, Willett WC. Dietary carotenoids and vitamins A, C, and
E and risk
of breast cancer. Department of Nutrition, Harvard School of Public Health,
Boston, MA 02115, USA. Shumin.Zhang@channing.harvard.edu J Natl Cancer Inst.
1999 Mar
17;91(6):547-56.
38. Kurbacher CM, Wagner U, Kolster B, Andreotti PE, Krebs D, Bruckner HW.
Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin,
cisplatin,
and paclitaxel in human breast carcinoma cells in vitro. Department of Gynecology
and Obstetrics, University of Bonn Medical Center, Germany. Cancer Lett.
1996 Jun 5;103(2):183-9.
39. Harakeh S, Jariwalla RJ, Pauling L. Suppression of human immunodeficiency
virus replication by ascorbate in chronically and acutely infected cells.
Proc Natl Acad SciUSA. 1990; 87:7245-7249.
- Rivas CI, Vera JC, Guaiquil VH, et al. Increased uptake and accumulation
of Vitamin C in human immunodeficiency virus 1-infected hematopoietic cell
lines.
J Biol Chem. 1997; 272:5814-5820.
40. Jacques PF, Chylack LT Jr, Hankinson SE, Khu PM, Rogers G, Friend J,
Tung W, Wolfe JK, Padhye N, Willett WC, Taylor A. Long-term nutrient intake
and
early age-related nuclear lens opacities. Laboratory for Nutrition and Vision,
Jean
Mayer US Department of Agriculture Human Nutrition Research Center on Aging,
Tufts University, 711 Washington St, Boston, MA 02111, USA. Arch Ophthalmol.
2001 Jul;119(7):1009-19.
41. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled,
clinical trial of high-dose supplementation with vitamins C and E and beta
carotene for age-related cataract and vision loss: AREDS report no. 9. Arch
Ophthalmol.
2001 Oct;119(10):1439-52.
42. Simon JA, Hudes ES. Serum ascorbic acid and other correlates of self-reported
cataract among older Americans. General Internal Medicine Section, Medical
Service, Veterans Affairs Medical Center, San Francisco, and University of
California
94121, USA. jasimon@itsa.ucsf.edu
J Clin Epidemiol. 1999 Dec;52(12):1207-11.
43. Jacques PF. The potential preventive effects of vitamins for cataract
and age-related macular degeneration. Jean Mayer-USDA Human Nutrition Research
Center on Aging, Tufts
University Boston, USA. Int J Vitam Nutr Res. 1999 May;69(3):198-205.
44. Weinstein M, Babyn P, Zlotkin S. An orange a day keeps the doctor away:
scurvy in the year 2000. Department of Paediatrics, Hospital for Sick Children
and University
of Toronto, Toronto, Canada. michael.weinstein@sickkids.on.ca Pediatrics.
2001 Sep;108(3):E55.
45. Food and Nutrition Board, Institute of Medicine. Vitamin C. Dietary Reference
Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington D.C.:
National Academy Press; 2000:95-185. (National Academy Press)
- Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids.
Washington, D.C.: National Academy Press; 2000.
- Markham RG. Compositions and methods for administering vitamin C. United
States Patent Number 4, 822, 816.
April 18, 1989.
Parerea din pasajele acestui site nu a fost independent cercetate
sau confirmate
|
Necesitatea folosirii Vitaminei C Acid ascorbic.
